What epitope does orticumab bind on oxLDL?
Orticumab recognizes and binds a specific epitope of oxLDL, [...]
What kind of molecule is orticumab?
Orticumab is a first-in-class fully-human IgG1 type antibody directed [...]
Recombinant Antibodies to an Oxidized Low-Density Lipoprotein Epitope Induce Rapid Regression of Atherosclerosis in Apobec-1-/- /Low-Density Lipoprotein Receptor-/- Mice
Schiopu et al, 2007, Journal of the American College [...]
Inhibition of injury-induced arterial remodeling and carotid atherosclerosis by recombinant human antibodies against aldehyde-modified apoB-100
Strom et al, 2007, Atherosclerosis Journal, Volume 190, ISSUE [...]
Identification of the target for therapeutic recombinant anti-apoB100 peptide antibodies in human atherosclerotic lesions
Goncalves et al, 2009, Atherosclerosis Journal, Volume 205, ISSUE [...]
Targeting oxidized LDL improves insulin sensitivity and immune cell function in obese Rhesus macaques
Li, S. et al, 2013, Molecular Metabolism, Volume 2, [...]
How can I prevent coronary artery disease?
You can reduce your risk of coronary artery disease by [...]
What treatments are available for coronary artery disease?
Treatment for coronary artery disease may include lifestyle changes such [...]
How is coronary artery disease diagnosed?
Diagnosis of coronary artery disease typically involves a combination of [...]
What are the symptoms of coronary artery disease?
The symptoms of coronary artery disease can vary depending on [...]
