Plaque-Targeted Anti-Inflammatory Therapy

Inflammation is the major driver of heart attacks for patients with coronary artery disease. Using a new therapeutic approach, we are addressing the problem in a highly specific manner to maximize benefit to patients while also minimizing the risks.

About Coronary Artery Disease
About Coronary Artery Disease
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Coronary Artery Disease (CAD) is the #1 cause of death worldwide.

CAD is the leading cause of death worldwide.  It is a condition characterized by the buildup of plaque in the arteries that supply blood to the heart muscle (a condition called atherosclerosis). This build-up causes inflammation, which often goes untreated, and ultimately leads to an acute coronary syndrome (ACS) event such as a heart attack or unstable angina.

0M
Patients in the US living with CAD
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Deaths in the US from CAD each year
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US hospitalizations for ACS annually

Coronary Inflammation causes heart attacks

For many decades, cardiologists have known that inflammation plays a key role in the development of CAD and causes heart attacks. Systemic treatments for inflammation can help, but also come with other potential serious risks and side effects.

Learn More About Coronary Inflammation

Abcentra’s Innovative Solution:

Treat Vascular Inflammation Locally

Abcentra’s targeted approach provides the ability to intervene with precision, which has promise to maximize the benefit to patients while minimizing the risks.

Orticumab is a first-in-class monoclonal antibody against oxidized LDL that targets vascular inflammation locally.

latest news & insights

Keep up with our work, find new resources, and stay on top of important news regarding the future of treatment for coronary artery disease.

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White quotation marks

Our mission to combat arterial inflammation isn’t just about developing a drug, it is about rewriting the narrative around cardiovascular health. We believe in a future where the message of every heartbeat is vitality – not vulnerability.

Chris Farina – CEO, Abcentra

Join our team at an event near you.

You can find our team at cardiovascular events around the globe.
Attend some of these events and use the form on our contact page to schedule a meeting.