Diagnosis of coronary artery disease typically involves a combination of medical history assessment, physical examination, and diagnostic tests. These tests may include blood tests to check cholesterol levels and other markers of heart health, electrocardiogram (ECG or EKG) to measure the heart’s electrical activity, echocardiogram to visualize the heart’s structure and function, stress tests, coronary angiography, cardiac CT scan, and others as determined by your healthcare provider.