The symptoms of coronary artery disease can vary depending on the specific condition but may include chest pain or discomfort (angina), shortness of breath, fatigue, dizziness, palpitations (irregular heartbeats), swelling in the legs, ankles, or abdomen, and fainting spells. A completely blocked coronary artery will cause a heart attack. The classic signs and symptoms of a heart attack include crushing chest pain or pressure, shoulder or arm pain, shortness of breath, and sweating. However, it’s important to note that some people with coronary artery disease may not experience any symptoms, especially in the early stages.